The name Otis has been used for five tropical cyclones in the Eastern Pacific Ocean.

• Hurricane Otis (1981) – a Category 1 hurricane that briefly impacted Mexico as a tropical storm
• Hurricane Otis (1987) – a Category 3 hurricane that stayed out to sea, causing no threat to land
• Hurricane Otis (2005) – a Category 2 hurricane that nearly threatened Baja California Sur
• Hurricane Otis (2017) – a Category 3 hurricane that stayed out to sea, causing no threat to land
• Hurricane Otis (2023) – a Category 5 hurricane that made landfall near Acapulco, Mexico; the strongest and most damaging hurricane ever recorded along the Pacific coast of North America, and the second-highest rate of intensification on record for the Western Hemisphere.