Ledol

Names
IUPAC name 6β,11-Cyclo-1β,4α,5β-guaian-10α-ol
Systematic IUPAC name (1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-Tetramethyldecahydro-1H-cyclopropa[e]azulen-4-ol
Identifiers
CAS Number	577-27-5 Y
3D model (JSmol)	Interactive image
ChemSpider	83783
PubChem CID	92812
UNII	99XJ3YS21U Y
CompTox Dashboard (EPA)	DTXSID40877915
InChI InChI=1S/C15H26O/c1-9-5-6-10-12(9)13-11(14(13,2)3)7-8-15(10,4)16/h9-13,16H,5-8H2,1-4H3/t9-,10+,11-,12-,13-,15-/m1/s1 Key: AYXPYQRXGNDJFU-AOWZIMASSA-N InChI=1/C15H26O/c1-9-5-6-10-12(9)13-11(14(13,2)3)7-8-15(10,4)16/h9-13,16H,5-8H2,1-4H3/t9-,10+,11-,12-,13-,15-/m1/s1 Key: AYXPYQRXGNDJFU-AOWZIMASBF
SMILES C[C@@H]1CC[C@H]2[C@@H]1[C@H]3[C@H](C3(C)C)CC[C@@]2(C)O
Properties
Chemical formula	C15H26O
Molar mass	222.372 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Ledol is a poisonous sesquiterpene that can cause cramps, paralysis, and delirium. Caucasian peasants used Rhododendron plants for these effects in shamanistic rituals.^[1]

Sources

Ledol is found in labrador tea, an herbal tea (not a true tea) made from three closely related species:

• Rhododendron tomentosum – Northern Labrador tea, previously Ledum palustre
• Rhododendron groenlandicum – Bog Labrador tea, previously Ledum groenlandicum or Ledum latifolium
• Rhododendron columbianum – Western Labrador tea, or trapper's tea, previously Ledum glandulosum

Ledol is also found in the essential oil of priprioca at a concentration of around 4%.^[2]

Ledol is also found to varying concentrations in the following plants:^[3]

References