RASAL3

RASAL3
Identifiers
Aliases	RASAL3, RAS protein activator like 3
External IDs	OMIM: 616561 MGI: 2444128 HomoloGene: 18901 GeneCards: RASAL3
Gene location (Human)
Chr.	Chromosome 19 (human)
End	15,464,544 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	32,622,557 bp
RNA expression pattern
	Top expressed in
	spleen; ; lymph node; ; appendix; ; blood; ; bone marrow cells; ; thymus; ; monocyte; ; upper lobe of left lung; ; right lung; ; pylorus;
	Top expressed in
	thymus; ; blood; ; spleen; ; subcutaneous adipose tissue; ; spermatocyte; ; pharynx; ; seminiferous tubule; ; duodenum; ; spermatid; ; Paneth cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase activator activity;
Cellular component	cytosol; membrane; intrinsic component of the cytoplasmic side of the plasma membrane; cytoplasmic side of membrane; cell cortex; extracellular exosome; cytoplasm;
Biological process	regulation of GTPase activity; MAPK cascade; positive regulation of NK T cell proliferation; signal transduction; negative regulation of Ras protein signal transduction; positive regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	64926
	320484
	ENSG00000105122
	ENSMUSG00000052142
	Q86YV0
	Q8C2K5
NM_022904; NM_001348027; NM_001348028; NM_001400377; NM_001400378;
	NM_001400379; NM_001400380; NM_001400381
	NM_178785; NM_001347343; NM_001374604; NM_001400382
	NP_075055; NP_001334956; NP_001334957
	NP_001334272; NP_848900; NP_001361533; NP_001387311
	Wikidata
View/Edit Human	View/Edit Mouse

RAS protein activator like 3 is a protein that in humans is encoded by the RASAL3 gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000105122 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052142 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: RAS protein activator like 3". Retrieved 2016-07-16.

Saito S, Kawamura T, Higuchi M, Kobayashi T, Yoshita-Takahashi M, Yamazaki M, Abe M, Sakimura K, Kanda Y, Kawamura H, Jiang S, Naito M, Yoshizaki T, Takahashi M, Fujii M (2015). "RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells". Eur. J. Immunol. 45 (5): 1512–23. doi:10.1002/eji.201444977. PMID 25652366.

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